5NC5
Crystal structure of AcrBZ in complex with antibiotic puromycin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Multidrug efflux pump subunit AcrB | polymer | 1049 | 113665.2 | 3 | UniProt (P31224) Pfam (PF00873) | Escherichia coli K-12 | AcrAB-TolC multidrug efflux pump subunit AcrB,Acridine resistance protein B |
| 2 | D, E (D, E) | DARPin | polymer | 169 | 18317.6 | 2 | Escherichia coli | ||
| 3 | F, G, H (F, G, H) | Multidrug efflux pump accessory protein AcrZ | polymer | 49 | 5304.4 | 3 | UniProt (P0AAX1) Pfam (PF10766) | Escherichia coli O157:H7 | AcrAB-TolC multidrug efflux pump accessory protein AcrZ,Acridine resistance protein Z |
| 4 | I, J, S (A) | DODECYL-BETA-D-MALTOSIDE | non-polymer | 510.6 | 3 | Chemie (LMT) | |||
| 5 | K, QA, T, UA, XA... (A, B, C) | DODECANE | non-polymer | 170.3 | 8 | Chemie (D12) PubChem (8182) PubChem (5359624) | |||
| 6 | AA, CB, DA, DB, EB... (B, C, A) | DECANE | non-polymer | 142.3 | 26 | Chemie (D10) PubChem (15600) | |||
| 7 | AB, BA, BB, CA, EA... (C, B, A) | nonane | non-polymer | 128.3 | 14 | Chemie (DD9) PubChem (8141) | |||
| 8 | PA (B) | PUROMYCIN | non-polymer | 471.5 | 1 | Chemie (PUY) PubChem (4984) PubChem (5891) PubChem (439530) PubChem (5351455) PubChem (5702164) PubChem (6602487) PubChem (6604191) PubChem (11953804) PubChem (16760051) PubChem (23615943) PubChem (25202279) PubChem (40469853) PubChem (177678906) PubChem (1712112) PubChem (44120104) PubChem (2724365) PubChem (51340256) PubChem (51340724) PubChem (1548891) PubChem (92403519) PubChem (6102313) PubChem (6560136) PubChem (6610289) PubChem (124504893) PubChem (57614967) PubChem (12193264) PubChem (12314760) PubChem (58811233) PubChem (58811244) PubChem (168313088) PubChem (170842883) PubChem (73952279) PubChem (91711144) PubChem (94860682) PubChem (94860683) PubChem (94860684) PubChem (95566333) PubChem (95907090) PubChem (97289755) PubChem (98617641) PubChem (124504894) PubChem (131676367) PubChem (134692731) PubChem (135391169) PubChem (137658626) PubChem (155061105) PubChem (162911390) PubChem (166947121) | |||
| 9 | WA (C) | HEXANE | non-polymer | 86.2 | 1 | Chemie (HEX) PubChem (8058) | |||
| 10 | JB, KB, LB, MB (A, B, C, D) | water | water | 18.0 | 98 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 393543.9 | |
| Non-Polymers* | Number of molecules | 53 |
| Total formula weight | 8947.1 | |
| All* | Total formula weight | 402491.1 |
