5NC5
Crystal structure of AcrBZ in complex with antibiotic puromycin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C | Multidrug efflux pump subunit AcrB | polymer | 1049 | 113665.2 | 3 | UniProt (P31224) Pfam (PF00873) In PDB | Escherichia coli K-12 | AcrAB-TolC multidrug efflux pump subunit AcrB,Acridine resistance protein B |
| 2 | D, E | DARPin | polymer | 169 | 18317.6 | 2 | Escherichia coli | ||
| 3 | F, G, H | Multidrug efflux pump accessory protein AcrZ | polymer | 49 | 5304.4 | 3 | UniProt (P0AAX1) Pfam (PF10766) In PDB | Escherichia coli O157:H7 | AcrAB-TolC multidrug efflux pump accessory protein AcrZ,Acridine resistance protein Z |
| 4 | A | DODECYL-BETA-D-MALTOSIDE | non-polymer | 510.6 | 3 | Chemie (LMT) | |||
| 5 | A, B, C | DODECANE | non-polymer | 170.3 | 8 | Chemie (D12) | |||
| 6 | B, C, A | DECANE | non-polymer | 142.3 | 26 | Chemie (D10) | |||
| 7 | C, B, A | nonane | non-polymer | 128.3 | 14 | Chemie (DD9) | |||
| 8 | B | PUROMYCIN | non-polymer | 471.5 | 1 | Chemie (PUY) | |||
| 9 | C | HEXANE | non-polymer | 86.2 | 1 | Chemie (HEX) | |||
| 10 | water | water | 18.0 | 98 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 393543.9 | |
| Non-Polymers* | Number of molecules | 53 |
| Total formula weight | 8947.1 | |
| All* | Total formula weight | 402491.1 |
