5NBQ

The structure of the tripartite complex between OspE, the C-terminal domains of factor H and C3dg

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C	Complement C3	polymer	294	32824.6	3	UniProt (P01024) Pfam (PF07678) In PDB	Homo sapiens (Human)	C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1
2	D, E, F	Complement factor H	polymer	127	14443.4	3	UniProt (P08603) Pfam (PF00084) In PDB	Homo sapiens (Human)	H factor 1
3	G, I	Outer surface protein E	polymer	129	14385.1	2	UniProt (Q45001) Pfam (PF02471) In PDB	Borreliella burgdorferi (Lyme disease spirochete)
4	H	Outer surface protein E,Outer surface protein E	polymer	134	14810.6	1	UniProt (Q45001) Pfam (PF02471) In PDB	Borreliella burgdorferi (Lyme disease spirochete)
5		water	water		18.0	2	Chemie (HOH)

Sequence modifications

A, B, C: 994 - 1287 (UniProt: P01024)

PDB	External Database	Details
Ala 1010	Cys 1010	engineered mutation

H: -86 - 42 (UniProt: Q45001)
H: 43 - 47 (PDB: 5NBQ)

Contents of the asymmetric unit

Polymers	Number of chains	9
	Total formula weight	185384.7
All*	Total formula weight	185384.7

*Water molecules are not included.