5NBQ
The structure of the tripartite complex between OspE, the C-terminal domains of factor H and C3dg
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Complement C3 | polymer | 294 | 32824.6 | 3 | UniProt (P01024) Pfam (PF07678) | Homo sapiens (Human) | C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1 |
| 2 | D, E, F (D, E, F) | Complement factor H | polymer | 127 | 14443.4 | 3 | UniProt (P08603) Pfam (PF00084) | Homo sapiens (Human) | H factor 1 |
| 3 | G, I (G, I) | Outer surface protein E | polymer | 129 | 14385.1 | 2 | UniProt (Q45001) Pfam (PF02471) | Borreliella burgdorferi (Lyme disease spirochete) | |
| 4 | H (H) | Outer surface protein E,Outer surface protein E | polymer | 134 | 14810.6 | 1 | UniProt (Q45001) Pfam (PF02471) | Borreliella burgdorferi (Lyme disease spirochete) | |
| 5 | J, K (G, I) | water | water | 18.0 | 2 | Chemie (HOH) |
Sequence modifications
A, B, C: 994 - 1287 (UniProt: P01024)
H: -86 - 42 (UniProt: Q45001)
H: 43 - 47 (PDB: 5NBQ)
| PDB | External Database | Details |
|---|---|---|
| Ala 1010 | Cys 1010 | engineered mutation |
H: 43 - 47 (PDB: 5NBQ)
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 185384.7 | |
| All* | Total formula weight | 185384.7 |
