5N9N
Crystal structure of human Protein kinase CK2 catalytic subunit in complex with the ATP-competitive, tight-binding dibenzofuran inhibitor TF85 (4a)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Casein kinase II subunit alpha | polymer | 335 | 40066.7 | 1 | UniProt (P68400) Pfam (PF00069) | Homo sapiens (Human) | CK II alpha |
| 2 | B (A) | (4~{Z})-7,9-bis(chloranyl)-4-[[(4-methoxyphenyl)amino]methylidene]-8-oxidanyl-1,2-dihydrodibenzofuran-3-one | non-polymer | 404.2 | 1 | Chemie (KC5) | |||
| 3 | C, D, E, F, G (A) | ACETATE ION | non-polymer | 59.0 | 5 | Chemie (ACT) | |||
| 4 | H, I, J, K, L (A) | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
| 5 | M (A) | water | water | 18.0 | 175 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 40066.7 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1159.9 | |
| All* | Total formula weight | 41226.7 |
