Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004674 | molecular_function | protein serine/threonine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | binding site for residue KC5 A 401 |
| Chain | Residue |
| A | ARG43 |
| A | ILE174 |
| A | ASP175 |
| A | ACT405 |
| A | HOH593 |
| A | LEU45 |
| A | VAL53 |
| A | VAL66 |
| A | LYS68 |
| A | PHE113 |
| A | GLU114 |
| A | VAL116 |
| A | MET163 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue ACT A 402 |
| Chain | Residue |
| A | ARG80 |
| A | ARG155 |
| A | LEU178 |
| A | ASN189 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue ACT A 403 |
| Chain | Residue |
| A | GLY90 |
| A | GLY91 |
| A | ASN93 |
| A | ILE94 |
| A | ARG172 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue ACT A 404 |
| Chain | Residue |
| A | ASP38 |
| A | ILE59 |
| A | PRO295 |
| A | GLU296 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue ACT A 405 |
| Chain | Residue |
| A | SER51 |
| A | VAL53 |
| A | HIS160 |
| A | KC5401 |
| A | HOH621 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue ACT A 406 |
| Chain | Residue |
| A | LYS229 |
| A | PHE232 |
| A | HOH509 |
| A | HOH510 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 407 |
| Chain | Residue |
| A | GLN36 |
| A | TYR39 |
| A | LEU41 |
| A | ASP103 |
| A | PRO104 |
| A | ALA110 |
| A | ARG280 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 408 |
| Chain | Residue |
| A | ARG10 |
| A | GLN310 |
| A | ARG312 |
| A | GLU317 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 409 |
| Chain | Residue |
| A | SER194 |
| A | ARG195 |
| A | GOL410 |
| A | HOH505 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 410 |
| Chain | Residue |
| A | ARG191 |
| A | ALA193 |
| A | LYS198 |
| A | GOL409 |
| A | HOH521 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 411 |
| Chain | Residue |
| A | LEU202 |
| A | LEU203 |
| A | ASN238 |
| A | TYR239 |
| A | PHE269 |
| A | HOH638 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 24 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGRGKYSEVFeAinitnnek..........VVVK |
| Chain | Residue | Details |
| A | LEU45-LYS68 | |
| site_id | PS00108 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. ImHrDVKphNVMI |
| Chain | Residue | Details |
| A | ILE152-ILE164 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 285 |
| Details | Domain: {"description":"Protein kinase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 5 |
| Details | Region: {"description":"Interaction with beta subunit","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor"} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 9 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
