5N8L

Structure of TRBP dsRBD 1 and 2 in complex with a 19 bp siRNA (Complex B)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	RISC-loading complex subunit TARBP2	polymer	215	23012.3	1	UniProt (Q15633) Pfam (PF00035) In PDB	Homo sapiens (Human)	TAR RNA-binding protein 2,Trans-activation-responsive RNA-binding protein
2	B	RNA (5'-R(*UP*UP*AP*AP*UP*UP*AP*UP*CP*UP*AP*UP*UP*CP*CP*GP*UP*AP*CP*UP*U)-3')	polymer	21	6534.8	1		synthetic construct
3	C	RNA (5'-R(*GP*UP*AP*CP*GP*GP*AP*AP*UP*AP*GP*AP*UP*AP*AP*UP*UP*AP*AP*UP*U)-3')	polymer	21	6747.1	1		synthetic construct

Sequence modifications

A: 16 - 227 (UniProt: Q15633)

PDB	External Database	Details
Gly 13	-	expression tag
Gly 14	-	expression tag
Ser 15	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	36294.2
All*	Total formula weight	36294.2

*Water molecules are not included.