5N8A

Structure of RPA70N in complex with PrimPol (fragment 480-560)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (X)	DNA-directed primase/polymerase protein	polymer	102	11161.8	1	UniProt (Q96LW4)	Homo sapiens (Human)	hPrimpol1,Coiled-coil domain-containing protein 111
2	B (A)	Replication protein A 70 kDa DNA-binding subunit	polymer	121	13353.6	1	UniProt (P27694) Pfam (PF04057)	Homo sapiens (Human)	RP-A p70,Replication factor A protein 1,RF-A protein 1,Single-stranded DNA-binding protein
3	C, D (X, A)	water	water		18.0	140	Chemie (HOH)

Sequence modifications

X: -68 - 12 (UniProt: Q96LW4)

PDB	External Database	Details
Met -89	-	initiating methionine
Gly -88	-	expression tag
Ser -87	-	expression tag
Ser -86	-	expression tag
His -85	-	expression tag
His -84	-	expression tag
His -83	-	expression tag
His -82	-	expression tag
His -81	-	expression tag
His -80	-	expression tag
Ser -79	-	expression tag
Ser -78	-	expression tag
Gly -77	-	expression tag
Leu -76	-	expression tag
Val -75	-	expression tag
Pro -74	-	expression tag
Arg -73	-	expression tag
Gly -72	-	expression tag
Ser -71	-	expression tag
His -70	-	expression tag
Met -69	-	expression tag

A: 1 - 120 (UniProt: P27694)

PDB	External Database	Details
His 0	-	expression tag
Arg 7	Glu 7	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	24515.4
All*	Total formula weight	24515.4

*Water molecules are not included.