5N7N

CRYSTAL STRUCTURE OF CATHEPSIN D ZYMOGEN FROM THE TICK IXODES RICINUS (IRCD1)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Putative cathepsin d	polymer	367	40225.2	4	UniProt (V5HCK7) Pfam (PF00026)	Ixodes ricinus (castor bean tick)
2	E, F, G, I, J... (A, B, C, D)	SULFATE ION	non-polymer		96.1	18	Chemie (SO4)
3	H, N, T, Z (A, B, C, D)	AMMONIUM ION	non-polymer		18.0	4	Chemie (NH4)
4	AA, BA, CA, DA (A, B, C, D)	water	water		18.0	147	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 361 (UniProt: V5HCK7)

PDB	External Database	Details
Val 39	Glu 60	conflict
Leu 182	Arg 203	conflict
Asn 249	Asp 270	conflict
His 362	-	expression tag
His 363	-	expression tag
His 364	-	expression tag
His 365	-	expression tag
His 366	-	expression tag
His 367	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	160900.8
Non-Polymers*	Number of molecules	22
	Total formula weight	1801.3
All*	Total formula weight	162702.0

*Water molecules are not included.