Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0005764 | cellular_component | lysosome |
| A | 0006508 | biological_process | proteolysis |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0005764 | cellular_component | lysosome |
| B | 0006508 | biological_process | proteolysis |
| B | 0008233 | molecular_function | peptidase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| C | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| C | 0005764 | cellular_component | lysosome |
| C | 0006508 | biological_process | proteolysis |
| C | 0008233 | molecular_function | peptidase activity |
| C | 0016787 | molecular_function | hydrolase activity |
| D | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| D | 0005764 | cellular_component | lysosome |
| D | 0006508 | biological_process | proteolysis |
| D | 0008233 | molecular_function | peptidase activity |
| D | 0016787 | molecular_function | hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 A 401 |
| site_id | AC2 |
| Number of Residues | 1 |
| Details | binding site for residue SO4 A 402 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 A 403 |
| Chain | Residue |
| A | ARG116 |
| A | LYS121 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue NH4 A 404 |
| Chain | Residue |
| A | LEU35 |
| A | SER103 |
| A | GLY104 |
| A | GLY134 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 B 401 |
| Chain | Residue |
| B | LYS205 |
| B | GLY206 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 402 |
| Chain | Residue |
| B | SER232 |
| B | LYS233 |
| B | SER234 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 B 403 |
| Chain | Residue |
| B | ARG95 |
| B | ASP157 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 404 |
| Chain | Residue |
| B | ARG116 |
| B | LYS121 |
| C | GLN267 |
| site_id | AC9 |
| Number of Residues | 1 |
| Details | binding site for residue SO4 B 405 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue NH4 B 406 |
| Chain | Residue |
| B | LEU35 |
| B | TYR101 |
| B | SER103 |
| B | GLY104 |
| B | GLY134 |
| site_id | AD2 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 B 407 |
| site_id | AD3 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 C 401 |
| Chain | Residue |
| C | LYS233 |
| C | SER234 |
| site_id | AD4 |
| Number of Residues | 1 |
| Details | binding site for residue SO4 C 402 |
| site_id | AD5 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 C 403 |
| site_id | AD6 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 C 404 |
| Chain | Residue |
| C | GLN352 |
| C | ARG354 |
| site_id | AD7 |
| Number of Residues | 5 |
| Details | binding site for residue NH4 C 405 |
| Chain | Residue |
| C | LEU35 |
| C | TYR101 |
| C | SER103 |
| C | GLY104 |
| C | GLY134 |
| site_id | AD8 |
| Number of Residues | 1 |
| Details | binding site for residue SO4 C 406 |
| site_id | AD9 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 D 401 |
| site_id | AE1 |
| Number of Residues | 1 |
| Details | binding site for residue SO4 D 402 |
| site_id | AE2 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 D 403 |
| Chain | Residue |
| D | LYS233 |
| D | SER234 |
| site_id | AE3 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 D 404 |
| Chain | Residue |
| D | VAL229 |
| D | SER230 |
| D | ALA231 |
| D | SER288 |
| D | PRO290 |
| site_id | AE4 |
| Number of Residues | 5 |
| Details | binding site for residue NH4 D 405 |
| Chain | Residue |
| D | LEU35 |
| D | TYR101 |
| D | SER103 |
| D | GLY104 |
| D | GLY134 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. VIFDTGSANLWL |
| Chain | Residue | Details |
| A | VAL55-LEU66 | |
