5N7E
Crystal structure of the Dbl-homology domain of Bcr-Abl in complex with monobody Mb(Bcr-DH_4).
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Mb(Bcr-DH_4) | polymer | 95 | 10121.2 | 1 | synthetic construct | ||
| 2 | B (B) | Breakpoint cluster region protein | polymer | 219 | 24901.5 | 1 | UniProt (P11274) Pfam (PF00621) | Homo sapiens (Human) | Renal carcinoma antigen NY-REN-26 |
| 3 | C, D (A, B) | water | water | 18.0 | 348 | Chemie (HOH) |
Sequence modifications
B: 487 - 702 (UniProt: P11274)
| PDB | External Database | Details |
|---|---|---|
| Gly 484 | - | expression tag |
| Ala 485 | - | expression tag |
| Met 486 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 35022.7 | |
| All* | Total formula weight | 35022.7 |
