5N5U
Structure of p-boronophenylalanyl tRNA synthetase in complex with p-boronophenylalanine and adenosine monophosphate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Tyrosine--tRNA ligase | polymer | 314 | 35976.7 | 1 | UniProt (Q57834) Pfam (PF00579) | Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) | Tyrosyl-tRNA synthetase,TyrRS |
| 2 | B (A) | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 1 | Chemie (AMP) PubChem (16397049) PubChem (16760266) PubChem (224) PubChem (40467049) PubChem (40469468) PubChem (34768) PubChem (44348067) PubChem (83862) PubChem (45358029) PubChem (46874558) PubChem (40459109) PubChem (57358045) PubChem (57879893) PubChem (57879902) PubChem (46875232) PubChem (446048) PubChem (515384) PubChem (638042) PubChem (177678969) PubChem (6083) PubChem (1549371) PubChem (5316444) PubChem (92144436) PubChem (5742864) PubChem (122197642) PubChem (12358354) PubChem (12163610) PubChem (12358355) PubChem (162290139) PubChem (162946266) PubChem (171699505) | |||
| 3 | C (A) | 4-Borono-L-phenylalanine | non-polymer | 209.0 | 1 | Chemie (7N8) PubChem (2734317) PubChem (53503) PubChem (150315) | |||
| 4 | D, E, F (A) | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) PubChem (312) | |||
| 5 | G (A) | water | water | 18.0 | 221 | Chemie (HOH) |
Sequence modifications
A: 1 - 306 (UniProt: Q57834)
| PDB | External Database | Details |
|---|---|---|
| Leu 6 | Met 6 | engineered mutation |
| Ser 32 | Tyr 32 | engineered mutation |
| Ala 65 | Leu 65 | engineered mutation |
| Met 70 | His 70 | engineered mutation |
| Ser 158 | Asp 158 | engineered mutation |
| Glu 162 | Leu 162 | engineered mutation |
| Arg 286 | Asp 286 | engineered mutation |
| Ser 307 | - | expression tag |
| Ala 308 | - | expression tag |
| His 309 | - | expression tag |
| His 310 | - | expression tag |
| His 311 | - | expression tag |
| His 312 | - | expression tag |
| His 313 | - | expression tag |
| His 314 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 35976.7 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 662.6 | |
| All* | Total formula weight | 36639.3 |
