Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| A | 0004831 | molecular_function | tyrosine-tRNA ligase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006412 | biological_process | translation |
| A | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| A | 0006437 | biological_process | tyrosyl-tRNA aminoacylation |
| A | 0016874 | molecular_function | ligase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | binding site for residue AMP A 401 |
| Chain | Residue |
| A | PHE35 |
| A | VAL195 |
| A | LEU196 |
| A | MET205 |
| A | 7N8402 |
| A | HOH514 |
| A | HOH522 |
| A | HOH524 |
| A | HIS42 |
| A | GLY44 |
| A | HIS45 |
| A | GLN48 |
| A | GLY169 |
| A | GLY170 |
| A | GLU172 |
| A | PRO194 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | binding site for residue 7N8 A 402 |
| Chain | Residue |
| A | GLY34 |
| A | GLU36 |
| A | ALA65 |
| A | ALA67 |
| A | MET70 |
| A | TYR151 |
| A | GLN155 |
| A | SER158 |
| A | GLU162 |
| A | GLN173 |
| A | AMP401 |
| A | HOH591 |
| A | HOH652 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 403 |
| Chain | Residue |
| A | ARG257 |
| A | HIS283 |
| A | ARG286 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 404 |
| Chain | Residue |
| A | VAL236 |
| A | GLU237 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 405 |
| Chain | Residue |
| A | ARG131 |
| A | HOH688 |
Functional Information from PROSITE/UniProt
| site_id | PS00178 |
| Number of Residues | 10 |
| Details | AA_TRNA_LIGASE_I Aminoacyl-transfer RNA synthetases class-I signature. P..SGkIHLGHY |
| Chain | Residue | Details |
| A | PRO37-TYR46 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 7 |
| Details | Region: {"description":"Tyrosine"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Region: {"description":"Interaction with t-RNA"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | Motif: {"description":"'HIGH' region"} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Motif: {"description":"'KMSKS' region"} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"12754495","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | Site: {"description":"Interaction with t-RNA"} |
