5N5H

Crystal structure of metallo-beta-lactamase VIM-1 in complex with ML302F inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Beta-lactamase VIM-1	polymer	253	26898.8	1	UniProt (Q9XAY4) Pfam (PF00753) In PDB	Pseudomonas aeruginosa	Class B carbapenemase VIM-1,Metallo-beta-lactamase,Metallo-beta-lactamase VIM-1,Metallobeta-lactamase,VIM-1,VIM-1 metallo-beta lactamase,VIM-1 metallo-beta-lactamase,VIM-1 protein
2	A	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
3	A	(2Z)-2-sulfanyl-3-(2,3,6-trichlorophenyl)prop-2-enoic acid	non-polymer		283.6	1	Chemie (S3C)
4		water	water		18.0	237	Chemie (HOH)

Sequence modifications

A: 21 - 266 (UniProt: Q9XAY4)

PDB	External Database	Details
Lys 267	-	expression tag
His 268	-	expression tag
His 269	-	expression tag
His 270	-	expression tag
His 271	-	expression tag
His 272	-	expression tag
His 273	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	26898.8
Non-Polymers*	Number of molecules	3
	Total formula weight	414.4
All*	Total formula weight	27313.1

*Water molecules are not included.