5N5H
Crystal structure of metallo-beta-lactamase VIM-1 in complex with ML302F inhibitor
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008800 | molecular_function | beta-lactamase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0017001 | biological_process | antibiotic catabolic process |
| A | 0042597 | cellular_component | periplasmic space |
| A | 0046677 | biological_process | response to antibiotic |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 301 |
| Chain | Residue |
| A | ASP118 |
| A | CYS198 |
| A | HIS240 |
| A | S3C303 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 302 |
| Chain | Residue |
| A | HIS114 |
| A | HIS116 |
| A | HIS179 |
| A | S3C303 |
| site_id | AC3 |
| Number of Residues | 13 |
| Details | binding site for residue S3C A 303 |
| Chain | Residue |
| A | TRP87 |
| A | HIS116 |
| A | ASP118 |
| A | HIS179 |
| A | CYS198 |
| A | ASN210 |
| A | HIS240 |
| A | ZN301 |
| A | ZN302 |
| A | HOH423 |
| A | HOH448 |
| A | HOH454 |
| A | PHE62 |
