5N49
BRPF2 in complex with Compound 7
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Bromodomain-containing protein 1 | polymer | 135 | 15753.0 | 2 | UniProt (O95696) Pfam (PF00439) In PDB | Homo sapiens (Human) | BR140-like protein,Bromodomain and PHD finger-containing protein 2 |
| 2 | B | 2-(1,3,6-trimethyl-2-oxidanylidene-benzimidazol-5-yl)benzo[de]isoquinoline-1,3-dione | non-polymer | 371.4 | 1 | Chemie (8LW) | |||
| 3 | water | water | 18.0 | 343 | Chemie (HOH) |
Sequence modifications
A, B: 555 - 688 (UniProt: O95696)
| PDB | External Database | Details |
|---|---|---|
| Ser 554 | - | expression tag |
| Met 555 | Val 555 | conflict |
| Glu 566 | Pro 566 | conflict |
| Arg 569 | Val 569 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 31506.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 371.4 | |
| All* | Total formula weight | 31877.4 |
