5N3W
Crystal structure of LTA4H bound to a selective inhibitor against LTB4 generation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Leukotriene A-4 hydrolase | polymer | 619 | 70407.1 | 1 | UniProt (P09960) Pfam (PF17900) Pfam (PF01433) Pfam (PF09127) | Homo sapiens (Human) | LTA-4 hydrolase,Leukotriene A(4) hydrolase |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C (A) | YTTERBIUM (III) ION | non-polymer | 173.0 | 1 | Chemie (YB) | |||
| 4 | D (A) | IMIDAZOLE | non-polymer | 69.1 | 1 | Chemie (IMD) | |||
| 5 | E (A) | 3-[2-(2-hydroxyphenyl)ethyl]-5-methoxy-phenol | non-polymer | 244.3 | 1 | Chemie (8KW) | |||
| 6 | F (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 7 | G (A) | water | water | 18.0 | 437 | Chemie (HOH) |
Sequence modifications
A: 0 - 610 (UniProt: P09960)
| PDB | External Database | Details |
|---|---|---|
| Val 611 | - | expression tag |
| Asp 612 | - | expression tag |
| His 613 | - | expression tag |
| His 614 | - | expression tag |
| His 615 | - | expression tag |
| His 616 | - | expression tag |
| His 617 | - | expression tag |
| His 618 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 70407.1 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 610.9 | |
| All* | Total formula weight | 71017.9 |
