5N18
Second Bromodomain (BD2) from Candida albicans Bdf1 bound to an imidazopyridine (compound 2)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Bromodomain-containing factor 1 | polymer | 109 | 12626.3 | 2 | UniProt (Q5A4W8) Pfam (PF00439) | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | |
| 2 | C (A) | 4-[8-methyl-3-[(4-methylphenyl)amino]imidazo[1,2-a]pyridin-2-yl]phenol | non-polymer | 329.4 | 1 | Chemie (8HZ) | |||
| 3 | D (B) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | E, F (A, B) | water | water | 18.0 | 273 | Chemie (HOH) |
Sequence modifications
A, B: 386 - 491 (UniProt: Q5A4W8)
| PDB | External Database | Details |
|---|---|---|
| Ala 383 | - | expression tag |
| Met 384 | - | expression tag |
| Gly 385 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 25252.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 421.5 | |
| All* | Total formula weight | 25674.2 |
