5N17
First Bromodomain (BD1) from Candida albicans Bdf1 bound to a dibenzothiazepinone (compound 3)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Bromodomain-containing factor 1 | polymer | 138 | 15537.0 | 2 | UniProt (Q5A4W8) Pfam (PF00439) | Candida albicans (Yeast) | |
| 2 | C, F (A, B) | (2~{S})-~{N}-(5-methyl-6-oxidanylidene-benzo[b][1,4]benzothiazepin-2-yl)oxolane-2-carboxamide | non-polymer | 354.4 | 2 | Chemie (8FK) | |||
| 3 | D, E (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 259 | Chemie (HOH) |
Sequence modifications
A, B: 193 - 327 (UniProt: Q5A4W8)
| PDB | External Database | Details |
|---|---|---|
| Ala 190 | - | expression tag |
| Met 191 | - | expression tag |
| Gly 192 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 31074.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 901.0 | |
| All* | Total formula weight | 31975.1 |
