5N10
Cucurbit[8]uril and 14-3-3 based binary bivalent supramolecular-protein assembly platform
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | F, C, D | Estrogen receptor | polymer | 15 | 1532.5 | 3 | UniProt (P03372) In PDB | Homo sapiens | ER,ER-alpha,Estradiol receptor,Nuclear receptor subfamily 3 group A member 1 |
| 2 | A | 14-3-3 protein beta/alpha | polymer | 246 | 28114.4 | 1 | UniProt (P31946) Pfam (PF00244) In PDB | Homo sapiens (Human) | Protein 1054,Protein kinase C inhibitor protein 1,KCIP-1 |
| 3 | B | 14-3-3 protein beta/alpha | polymer | 249 | 28386.6 | 1 | UniProt (P31946) Pfam (PF00244) In PDB | Homo sapiens (Human) | Protein 1054,Protein kinase C inhibitor protein 1,KCIP-1 |
| 4 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | C | Cucurbit[8]uril | non-polymer | 1329.1 | 1 | Chemie (C8L) | |||
| 6 | water | water | 18.0 | 552 | Chemie (HOH) |
Sequence modifications
F, C, D: 584 - 595 (UniProt: P03372)
B: 1 - 246 (UniProt: P31946)
| PDB | External Database | Details |
|---|---|---|
| Phe 581 | - | expression tag |
| Gly 582 | - | expression tag |
| Gly 583 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gln -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 61098.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1421.2 | |
| All* | Total formula weight | 62519.8 |
