5N06

Crystal structure of Tie1 Fibronectin-like domain 3

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Tyrosine-protein kinase receptor Tie-1	polymer	126	14066.9	2	UniProt (P35590) Pfam (PF00041) In PDB	Homo sapiens (Human)
2		water	water		18.0	73	Chemie (HOH)

Sequence modifications

A, B: 642 - 738 (UniProt: P35590)

PDB	External Database	Details
Met 619	-	expression tag
Lys 620	-	expression tag
Phe 621	-	expression tag
Leu 622	-	expression tag
Val 623	-	expression tag
Asn 624	-	expression tag
Val 625	-	expression tag
Ala 626	-	expression tag
Leu 627	-	expression tag
Val 628	-	expression tag
Phe 629	-	expression tag
Met 630	-	expression tag
Val 631	-	expression tag
Val 632	-	expression tag
Tyr 633	-	expression tag
Ile 634	-	expression tag
Ser 635	-	expression tag
Tyr 636	-	expression tag
Ile 637	-	expression tag
Tyr 638	-	expression tag
Ala 639	-	cloning artifact
Asp 640	-	cloning artifact
Pro 641	-	cloning artifact
His 739	-	expression tag
His 740	-	expression tag
His 741	-	expression tag
His 742	-	expression tag
His 743	-	expression tag
His 744	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	28133.8
All*	Total formula weight	28133.8

*Water molecules are not included.