5MYB
Homodimerization of Tie2 Fibronectin-like domains 2 and 3 in space group P21
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Angiopoietin-1 receptor | polymer | 333 | 37583.3 | 2 | UniProt (Q02763) Pfam (PF00041) In PDB | Homo sapiens (Human) | Endothelial tyrosine kinase,Tunica interna endothelial cell kinase,Tyrosine kinase with Ig and EGF homology domains-2,Tyrosine-protein kinase receptor TEK,Tyrosine-protein kinase receptor TIE-2,hTIE2,p140 TEK |
| 2 | C | beta-D-mannopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G44266EX) | |||
| 3 | D | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 4 | A, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) | |||
| 5 | water | water | 18.0 | 62 | Chemie (HOH) |
Sequence modifications
A, B: 443 - 742 (UniProt: Q02763)
| PDB | External Database | Details |
|---|---|---|
| Met 420 | - | initiating methionine |
| Lys 421 | - | expression tag |
| Phe 422 | - | expression tag |
| Leu 423 | - | expression tag |
| Val 424 | - | expression tag |
| Asn 425 | - | expression tag |
| Val 426 | - | expression tag |
| Ala 427 | - | expression tag |
| Leu 428 | - | expression tag |
| Val 429 | - | expression tag |
| Phe 430 | - | expression tag |
| Met 431 | - | expression tag |
| Val 432 | - | expression tag |
| Val 433 | - | expression tag |
| Tyr 434 | - | expression tag |
| Ile 435 | - | expression tag |
| Ser 436 | - | expression tag |
| Tyr 437 | - | expression tag |
| Ile 438 | - | expression tag |
| Tyr 439 | - | expression tag |
| Ala 440 | - | expression tag |
| Asp 441 | - | expression tag |
| Pro 442 | - | expression tag |
| Ile 743 | - | expression tag |
| Glu 744 | - | expression tag |
| Gly 745 | - | expression tag |
| Arg 746 | - | expression tag |
| His 747 | - | expression tag |
| His 748 | - | expression tag |
| His 749 | - | expression tag |
| His 750 | - | expression tag |
| His 751 | - | expression tag |
| His 752 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 75166.6 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1010.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 884.8 | |
| All* | Total formula weight | 77062.4 |
