5MYA
Homodimerization of Tie2 Fibronectin-like domains 1-3 in space group C2
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Angiopoietin-1 receptor | polymer | 333 | 37583.3 | 2 | UniProt (Q02763) Pfam (PF00041) In PDB | Homo sapiens (Human) | Endothelial tyrosine kinase,Tunica interna endothelial cell kinase,Tyrosine kinase with Ig and EGF homology domains-2,Tyrosine-protein kinase receptor TEK,Tyrosine-protein kinase receptor TIE-2,hTIE2,p140 TEK |
2 | C | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
3 | D | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G81315DD) | |||
4 | E | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
5 | A, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) | |||
6 | water | water | 18.0 | 63 | Chemie (HOH) |
Sequence modifications
A, B: 443 - 742 (UniProt: Q02763)
PDB | External Database | Details |
---|---|---|
Met 420 | - | initiating methionine |
Lys 421 | - | expression tag |
Phe 422 | - | expression tag |
Leu 423 | - | expression tag |
Val 424 | - | expression tag |
Asn 425 | - | expression tag |
Val 426 | - | expression tag |
Ala 427 | - | expression tag |
Leu 428 | - | expression tag |
Val 429 | - | expression tag |
Phe 430 | - | expression tag |
Met 431 | - | expression tag |
Val 432 | - | expression tag |
Val 433 | - | expression tag |
Tyr 434 | - | expression tag |
Ile 435 | - | expression tag |
Ser 436 | - | expression tag |
Tyr 437 | - | expression tag |
Ile 438 | - | expression tag |
Tyr 439 | - | expression tag |
Ala 440 | - | expression tag |
Asp 441 | - | expression tag |
Pro 442 | - | expression tag |
Ile 743 | - | expression tag |
Glu 744 | - | expression tag |
Gly 745 | - | expression tag |
Arg 746 | - | expression tag |
His 747 | - | expression tag |
His 748 | - | expression tag |
His 749 | - | expression tag |
His 750 | - | expression tag |
His 751 | - | expression tag |
His 752 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 75166.6 | |
Branched | Number of molecules | 3 |
Total formula weight | 1759.6 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 884.8 | |
All* | Total formula weight | 77811.1 |