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5MXR

Crystal Structure of the Acquired VIM-2 Metallo-beta-Lactamase in Complex with ANT-330 Inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Beta-lactamase VIM-2polymer23224766.51UniProt (Q9K2N0)
Pfam (PF00753)
Pseudomonas aeruginosaClass B beta-lactamase,Class B carbapenemase VIM-2,Metallo beta lactamase VIM-2,Metallo beta-lactamase,Metallo-beta-lactamase,Metallo-beta-lactamase VIM-2,Metallo-beta-lactamase vim-2,VIM-2 metallo-beta-lactamase,VIM-2 protein
2B, C, D
(A)
ZINC IONnon-polymer65.43Chemie (ZN)
3E
(A)
ACETATE IONnon-polymer59.01Chemie (ACT)
4F, G
(A)
5-(phenylsulfonylamino)-1,3-thiazole-4-carboxylic acidnon-polymer284.32Chemie (JTY)
5H
(A)
waterwater18.0120Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight24766.5
Non-Polymers*Number of molecules6
Total formula weight823.9
All*Total formula weight25590.4
*Water molecules are not included.

239803

PDB entries from 2025-08-06

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