5MWB

Human Notch-2 EGF11-13

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Neurogenic locus notch homolog protein 2	polymer	156	17145.3	1	UniProt (Q04721) Pfam (PF07645) Pfam (PF00008)	Homo sapiens (Human)	hN2
2	B (B)	beta-D-xylopyranose-(1-3)-beta-D-glucopyranose	branched		312.3	1	In PDB GlyTouCan (G61966PH)
3	C (A)	alpha-L-fucopyranose	non-polymer		164.2	1	Chemie (FUC)
4	D (A)	beta-D-glucopyranose	non-polymer		180.2	1	Chemie (BGC)
5	E, F, G (A)	CALCIUM ION	non-polymer		40.1	3	Chemie (CA)
6	H (A)	water	water		18.0	121	Chemie (HOH)

Sequence modifications

A: 414 - 532 (UniProt: Q04721)

PDB	External Database	Details
Gly 533	-	expression tag
Ser 534	-	expression tag
Gly 535	-	expression tag
Leu 536	-	expression tag
Glu 537	-	expression tag
Val 538	-	expression tag
Leu 539	-	expression tag
Phe 540	-	expression tag
Gln 541	-	expression tag
Gly 542	-	expression tag
Pro 543	-	expression tag
Gly 544	-	expression tag
Ser 545	-	expression tag
Leu 546	-	expression tag
His 547	-	expression tag
His 548	-	expression tag
Ile 549	-	expression tag
Leu 550	-	expression tag
Asp 551	-	expression tag
Ala 552	-	expression tag
Gln 553	-	expression tag
Lys 554	-	expression tag
Met 555	-	expression tag
Val 556	-	expression tag
Trp 557	-	expression tag
Asn 558	-	expression tag
His 559	-	expression tag
Arg 560	-	expression tag
Gly 561	-	expression tag
His 562	-	expression tag
His 563	-	expression tag
His 564	-	expression tag
His 565	-	expression tag
His 566	-	expression tag
His 567	-	expression tag
His 568	-	expression tag
His 569	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	17145.3
Branched	Number of molecules	1
	Total formula weight	312.3
Non-Polymers*	Number of molecules	5
	Total formula weight	464.5
All*	Total formula weight	17922.1

*Water molecules are not included.