5MW2
CRYSTAL STRUCTURE OF BCL-6 BTB-domain with BI-3802
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | B-cell lymphoma 6 protein | polymer | 126 | 14502.8 | 1 | UniProt (P41182) Pfam (PF00651) | Homo sapiens (Human) | BCL-6,B-cell lymphoma 5 protein,BCL-5,Protein LAZ-3,Zinc finger and BTB domain-containing protein 27,Zinc finger protein 51 |
| 2 | B (A) | 2-[6-[[5-chloranyl-2-[(3~{S},5~{R})-3,5-dimethylpiperidin-1-yl]pyrimidin-4-yl]amino]-1-methyl-2-oxidanylidene-quinolin-3-yl]oxy-~{N}-methyl-ethanamide | non-polymer | 485.0 | 1 | Chemie (U52) | |||
| 3 | C (A) | water | water | 18.0 | 14 | Chemie (HOH) |
Sequence modifications
A: 5 - 129 (UniProt: P41182)
| PDB | External Database | Details |
|---|---|---|
| Ser 4 | - | expression tag |
| Gln 8 | Cys 8 | conflict |
| Arg 67 | Cys 67 | conflict |
| Asn 84 | Cys 84 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 14502.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 485.0 | |
| All* | Total formula weight | 14987.7 |
