5MVZ

Fab 4AB007 bound to Interleukin-1-beta

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	H, A	Fab 4AB007 H-chain	polymer	240	25437.9	2		Homo sapiens (Human)
2	L, B	Fab 4AB007 L-chain	polymer	249	27678.8	2		Homo sapiens (Human)
3	U, V	Interleukin-1 beta	polymer	177	20333.0	2	UniProt (B5BUQ8) Pfam (PF00340) UniProt (by SIFTS) (P01584) In PDB	Homo sapiens (Human)
4	H, L, A, B	GLYCEROL	non-polymer		92.1	8	Chemie (GOL)
5		water	water		18.0	634	Chemie (HOH)

Sequence modifications

U, V: 1 - 153 (UniProt: B5BUQ8)

PDB	External Database	Details
Met -23	-	initiating methionine
Ala -22	-	expression tag
His -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Pro -9	-	expression tag
Ala -8	-	expression tag
Gly -7	-	expression tag
Glu -6	-	expression tag
Asn -5	-	expression tag
Leu -4	-	expression tag
Tyr -3	-	expression tag
Phe -2	-	expression tag
Gln -1	-	expression tag
Gly 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	146899.4
Non-Polymers*	Number of molecules	8
	Total formula weight	736.8
All*	Total formula weight	147636.1

*Water molecules are not included.