5MUR
X-ray structure of the F14'A mutant of GLIC in complex with propofol
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E | Proton-gated ion channel | polymer | 317 | 36201.6 | 5 | UniProt (Q7NDN8) Pfam (PF02931) In PDB | Gloeobacter violaceus (strain PCC 7421) | GLIC,Ligand-gated ion channel,LGIC |
| 2 | D, E, A, B, C | ACETATE ION | non-polymer | 59.0 | 10 | Chemie (ACT) | |||
| 3 | E, A, B, C, D | CHLORIDE ION | non-polymer | 35.5 | 5 | Chemie (CL) | |||
| 4 | E, A, B, C, D | SODIUM ION | non-polymer | 23.0 | 6 | Chemie (NA) | |||
| 5 | E, A, B, C, D | DIUNDECYL PHOSPHATIDYL CHOLINE | non-polymer | 622.8 | 5 | Chemie (PLC) | |||
| 6 | E, B | 2,6-BIS(1-METHYLETHYL)PHENOL | non-polymer | 178.3 | 2 | Chemie (PFL) | |||
| 7 | water | water | 18.0 | 122 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E: 1 - 317 (UniProt: Q7NDN8)
| PDB | External Database | Details |
|---|---|---|
| Ala 238 | Phe 280 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 181008.1 | |
| Non-Polymers* | Number of molecules | 28 |
| Total formula weight | 4376.4 | |
| All* | Total formula weight | 185384.5 |
