5MU8
HUMAN TNF-ALPHA IN COMPLEX WITH JNJ525
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, AA, B, BA, C... (A, B, C, D, F...) | Tumor necrosis factor | polymer | 159 | 17572.9 | 48 | UniProt (P01375) Pfam (PF00229) | Homo sapiens (Human) | Cachectin,TNF-alpha,Tumor necrosis factor ligand superfamily member 2,TNF-a |
| 2 | AB, AC, BB, BC, CB... (D, h, F, j, H...) | ~{N}4-(phenylmethyl)-~{N}4-[2-[3-(2-piperazin-1-ylpyrimidin-5-yl)phenyl]phenyl]pyrimidine-2,4-diamine | non-polymer | 514.6 | 46 | Chemie (JNI) |
Sequence modifications
A, B, C, D, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X, Y, Z, a, b, c, d, e, f, g, h, i, j, k, l, m, n, o, p, q, r, s, t, u, v, w: 1 - 157 (UniProt: P01375)
| PDB | External Database | Details |
|---|---|---|
| Ala -1 | - | expression tag |
| Met 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 48 |
| Total formula weight | 843500.7 | |
| Non-Polymers* | Number of molecules | 46 |
| Total formula weight | 23672.7 | |
| All* | Total formula weight | 867173.4 |
