5MP3
Crystal structure of DC8E8 Fab in the complex with a 30-mer tau peptide at pH 6.5
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (H, A) | Igh protein | polymer | 220 | 23685.5 | 2 | UniProt (Q99LC4) Pfam (PF07686) Pfam (PF07654) | Mus musculus (Mouse) | |
| 2 | B, D (L, B) | ENSMUSG00000076577 protein | polymer | 218 | 24172.8 | 2 | UniProt (Q52L64) Pfam (PF07686) Pfam (PF07654) | Mus musculus (Mouse) | |
| 3 | E, F (C, D) | Microtubule-associated protein | polymer | 30 | 3144.6 | 2 | UniProt (A0A024R9Y0) Pfam (PF00418) UniProt (by SIFTS) (P10636) | Homo sapiens | |
| 4 | G, H, I, J, K (H, L, A, B, D) | water | water | 18.0 | 58 | Chemie (HOH) |
Sequence modifications
H, A: 2 - 220 (UniProt: Q99LC4)
L, B: 1 - 218 (UniProt: Q52L64)
| PDB | External Database | Details |
|---|---|---|
| Pca 1 | - | expression tag |
| Pro 9 | Ala 28 | conflict |
| Val 12 | Ala 31 | conflict |
| Lys 13 | Arg 32 | conflict |
| Thr 16 | Ala 35 | conflict |
| Lys 19 | Arg 38 | conflict |
| Met 20 | Leu 39 | conflict |
| Pro 21 | Ser 40 | conflict |
| Ile 28 | Thr 47 | conflict |
| Asp 31 | Gly 50 | conflict |
| Val 33 | Gly 52 | conflict |
| Ile 34 | Val 53 | conflict |
| Ile 48 | Val 67 | conflict |
| Phe 52 | Tyr 71 | conflict |
| Arg 54 | Gly 73 | conflict |
| Ser 57 | Asn 76 | conflict |
| Asn 61 | Ser 80 | conflict |
| Ala 72 | Thr 91 | conflict |
| Asn 77 | Ser 96 | conflict |
| Gln 82 | His 101 | conflict |
| Val 86 | Leu 105 | conflict |
| Asp 99 | Ser 118 | conflict |
| Tyr 100 | Ser 119 | conflict |
| Gly 102 | Tyr 121 | conflict |
| Thr 103 | Ser 122 | conflict |
| Ser 104 | Tyr 123 | conflict |
| Phe 105 | Asp 124 | conflict |
| Ala 106 | Leu 125 | conflict |
| Met 107 | Phe 126 | conflict |
| Asp 108 | Ala 127 | conflict |
| Ser 115 | Leu 134 | conflict |
| Ser 120 | Ala 139 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ala 15 | Val 35 | conflict |
| Asn 31 | Tyr 51 | conflict |
| Arg 33 | Tyr 53 | conflict |
| Thr 34 | Asn 54 | conflict |
| Arg 35 | Gln 55 | conflict |
| Arg 67 | His 87 | conflict |
| Thr 69 | Ser 89 | conflict |
| Gln 85 | Lys 105 | conflict |
| Val 91 | Leu 111 | conflict |
| Lys 95 | Gln 115 | conflict |
| - | Tyr 117 | deletion |
| Ser 97 | Tyr 118 | conflict |
| Phe 98 | Asn 119 | conflict |
| Leu 100 | Pro 121 | conflict |
| Arg 101 | Leu 122 | conflict |
| Gly 105 | Ala 126 | conflict |
| Ile 111 | Leu 132 | conflict |
| Lys 112 | Arg 133 | conflict |
| Arg 152 | Lys 173 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 102005.9 | |
| All* | Total formula weight | 102005.9 |
