5MOK
Crystal structure of human IgE-Fc epsilon 3-4
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Ig epsilon chain C region | polymer | 223 | 24920.1 | 4 | UniProt (P01854) Pfam (PF07654) | Homo sapiens (Human) | |
| 2 | E (E) | alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G22573RC) | |||
| 3 | F, H (F, H) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1235.1 | 2 | In PDB GlyTouCan (G55220VL) | |||
| 4 | G (G) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 707.6 | 1 | In PDB GlyTouCan (G00027MO) | |||
| 5 | I, N (A, D) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
| 6 | J, K, L, M, O (A, C, D) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
| 7 | P, Q, R, S (A, B, C, D) | water | water | 18.0 | 519 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 328 - 547 (UniProt: P01854)
| PDB | External Database | Details |
|---|---|---|
| Ala 325 | - | expression tag |
| Asp 326 | - | expression tag |
| Pro 327 | - | expression tag |
| Gln 371 | Asn 252 | conflict |
| Gln 383 | Asn 264 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 99680.6 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 3926.5 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 522.6 | |
| All* | Total formula weight | 104129.7 |
