5MO3
Crystal structure of DC8E8 Fab in the complex with a 14-mer tau peptide at pH 8.5
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Microtubule-associated protein tau | polymer | 14 | 1471.7 | 1 | UniProt (P10636) | Homo sapiens | Neurofibrillary tangle protein,Paired helical filament-tau,PHF-tau |
| 2 | B (H) | Fab of monoclonal antibody, heavy chain | polymer | 221 | 23800.6 | 1 | Mus musculus (House Mouse) | ||
| 3 | C (L) | Fab of monoclonal antibody, light chain | polymer | 218 | 24172.8 | 1 | Mus musculus (House Mouse) | ||
| 4 | D (B) | alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose | branched | 342.3 | 1 | In PDB BIRD (PRD_900006) GlyTouCan (G92130SN) | trehalose | ||
| 5 | E, F, G, H (H, L) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 4 | Chemie (PGE) | |||
| 6 | I, J (H, L) | water | water | 18.0 | 403 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 49445.1 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 342.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 600.7 | |
| All* | Total formula weight | 50388.1 |
