5MN2
Cocrystal structure of Fc gamma receptor IIIa interacting with Affimer G3, a specific binding protein which blocks IgG binding to the receptor.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Low affinity immunoglobulin gamma Fc region receptor III-A | polymer | 175 | 20076.4 | 2 | UniProt (P08637) Pfam (PF13895) | Homo sapiens (Human) | CD16a antigen,Fc-gamma RIII-alpha,FcRIIIa,FcR-10,IgG Fc receptor III-2 |
| 2 | C, D (C, D) | Affimer G3 | polymer | 101 | 11521.2 | 2 | synthetic construct | ||
| 3 | E, F, G, H, I... (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 7 | Chemie (NAG) | |||
| 4 | J, N (A, B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
| 5 | K (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 6 | O (D) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
| 7 | P, Q, R, S (A, B, C, D) | water | water | 18.0 | 146 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 63195.1 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 2047.0 | |
| All* | Total formula weight | 65242.1 |
