5MKE
cryoEM Structure of Polycystin-2 in complex with cations and lipids
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Polycystin-2 | polymer | 968 | 109820.1 | 4 | UniProt (Q13563) Pfam (PF20519) Pfam (PF00520) Pfam (PF08016) Pfam (PF18109) In PDB | Homo sapiens (Human) | Autosomal dominant polycystic kidney disease type II protein,Polycystic kidney disease 2 protein,Polycystwin,R48321,Transient receptor potential cation channel subfamily P member 2 |
| 2 | E, F, G | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 3 | In PDB GlyTouCan (G42666HT) | |||
| 3 | C, A, D, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 10 | Chemie (NAG) | |||
| 4 | C, A, D, B | 4-AMINO-5-CYCLOHEXYL-3-HYDROXY-PENTANOIC ACID | non-polymer | 215.3 | 8 | Chemie (CHS) | |||
| 5 | C, A, D, B | 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHATE | non-polymer | 647.9 | 4 | Chemie (PX6) | |||
| 6 | C, A, D, B | PALMITIC ACID | non-polymer | 256.4 | 12 | Chemie (PLM) | |||
| 7 | A | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 439280.3 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 1273.2 | |
| Non-Polymers* | Number of molecules | 36 |
| Total formula weight | 9683.2 | |
| All* | Total formula weight | 450236.7 |
