5MKE

cryoEM Structure of Polycystin-2 in complex with cations and lipids

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Polycystin-2	polymer	968	109820.1	4	UniProt (Q13563) Pfam (PF20519) Pfam (PF00520) Pfam (PF08016) Pfam (PF18109)	Homo sapiens (Human)	Autosomal dominant polycystic kidney disease type II protein,Polycystic kidney disease 2 protein,Polycystwin,R48321,Transient receptor potential cation channel subfamily P member 2
2	E, F, G (E, F, G)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	3	In PDB GlyTouCan (G42666HT)
3	AA, H, HA, I, IA... (C, A, D, B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	10	Chemie (NAG)
4	BA, CA, J, K, LA... (C, A, D, B)	4-AMINO-5-CYCLOHEXYL-3-HYDROXY-PENTANOIC ACID	non-polymer		215.3	8	Chemie (CHS)
5	DA, L, NA, V (C, A, D, B)	1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHATE	non-polymer		647.9	4	Chemie (PX6)
6	EA, FA, GA, M, N... (C, A, D, B)	PALMITIC ACID	non-polymer		256.4	12	Chemie (PLM)
7	P, Q (A)	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	439280.3
Branched	Number of molecules	3
	Total formula weight	1273.2
Non-Polymers*	Number of molecules	36
	Total formula weight	9683.2
All*	Total formula weight	450236.7

*Water molecules are not included.