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5MJ5

Crystal structure of the Retinoid X Receptor alpha in complex with synthetichonokiol derivative 3 and a fragment of the TIF2 co-activator.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Retinoic acid receptor RXR-alphapolymer22925670.81UniProt (P19793)
Pfam (PF00104)
Homo sapiens (Human)Nuclear receptor subfamily 2 group B member 1,Retinoid X receptor alpha
2B
(B)
LYS-HIS-LYS-ILE-LEU-HIS-ARG-LEU-LEU-GLN-ASP-SERpolymer131579.91Homo sapiens
3C
(A)
(~{E})-3-[4-oxidanyl-3-[3-(phenylmethyl)phenyl]phenyl]prop-2-enoic acidnon-polymer330.41Chemie (7O0)
4D, E
(A, B)
waterwater18.0127Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight27250.7
Non-Polymers*Number of molecules1
Total formula weight330.4
All*Total formula weight27581.0
*Water molecules are not included.

238895

PDB entries from 2025-07-16

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