5MI0

A thermally stabilised version of Plasmodium falciparum RH5

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Reticulocyte binding-like protein 5,Reticulocyte binding protein 5	polymer	360	43842.4	1	UniProt (A0A159SJI5) UniProt (B2L3N7) Pfam (PF18515) UniProt (by SIFTS) (Q8IFM5)	Plasmodium falciparum
2	B (B)	MONOCLONAL ANTIBODY 9AD4	polymer	258	27641.2	1		Mus musculus
3	C (C)	MONOCLONAL ANTIBODY 9AD4	polymer	238	26259.3	1		Mus musculus
4	D, E, F (A, B, C)	water	water		18.0	261	Chemie (HOH)

Sequence modifications

A: 140 - 296 (UniProt: A0A159SJI5)

PDB	External Database	Details
His 124	-	expression tag
His 125	-	expression tag
His 126	-	expression tag
His 127	-	expression tag
His 128	-	expression tag
His 129	-	expression tag
Glu 130	-	expression tag
Asn 131	-	expression tag
Leu 132	-	expression tag
Tyr 133	-	expression tag
Phe 134	-	expression tag
Gln 135	-	expression tag
Gly 136	-	expression tag
Gly 137	-	expression tag
Ser 138	-	expression tag
Met 139	-	expression tag
Leu 157	Ile 130	conflict
Glu 183	Asp 156	conflict
Ala 216	Thr 189	conflict
Lys 233	Ala 206	conflict

A: 297 - 526 (UniProt: B2L3N7)

PDB	External Database	Details
Ala 299	Thr 299	conflict
Phe 304	Met 304	conflict
Asn 312	Lys 312	conflict
Phe 314	Leu 314	conflict
Asn 316	Lys 316	conflict
Asn 330	Met 330	conflict
Ala 370	Ser 370	conflict
Asn 381	Ser 381	conflict
Lys 384	Thr 384	conflict
Lys 392	Leu 392	conflict
Asn 395	Thr 395	conflict
Glu 398	Asn 398	conflict
Lys 458	Arg 458	conflict
Lys 464	Asn 464	conflict
Ala 467	Ser 467	conflict
Leu 505	Phe 505	conflict
His 527	-	expression tag
His 528	-	expression tag
His 529	-	expression tag
His 530	-	expression tag
His 531	-	expression tag
His 532	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	97742.9
All*	Total formula weight	97742.9

*Water molecules are not included.