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5MGV

Kinetic and Structural Changes in HsmtPheRS, Induced by Pathogenic Mutations in Human FARS2

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1APhenylalanine--tRNA ligase, mitochondrialpolymer40547519.91UniProt (O95363)
Pfam (PF01409)
Pfam (PF03147)
In PDB
Homo sapiens (Human)Phenylalanyl-tRNA synthetase,PheRS
2waterwater18.0249Chemie (HOH)
Sequence modifications
A: 11 - 415 (UniProt: O95363)
PDBExternal DatabaseDetails
Tyr 289Asp 325engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight47519.9
All*Total formula weight47519.9
*Water molecules are not included.

222624

PDB entries from 2024-07-17

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