5MGU
Kinetic and Structural Changes in HsmtPheRS, Induced by Pathogenic Mutations in Human FARS2
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Phenylalanine--tRNA ligase, mitochondrial | polymer | 407 | 47644.1 | 1 | UniProt (O95363) Pfam (PF01409) Pfam (PF03147) In PDB | Homo sapiens (Human) | Phenylalanyl-tRNA synthetase,PheRS |
2 | A | PHENYLALANINE | non-polymer | 165.2 | 1 | Chemie (PHE) | |||
3 | water | water | 18.0 | 235 | Chemie (HOH) |
Sequence modifications
A: 10 - 415 (UniProt: O95363)
PDB | External Database | Details |
---|---|---|
Ala 9 | - | expression tag |
Met 210 | Thr 246 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 47644.1 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 165.2 | |
All* | Total formula weight | 47809.3 |