5MEY
Crystal structure of Smad4-MH1 bound to the GGCGC site.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | MH1 domain of human Smad4 | polymer | 135 | 15237.6 | 1 | UniProt (Q13485) Pfam (PF03165) | Homo sapiens (Human) | Mothers against DPP homolog 4,Deletion target in pancreatic carcinoma 4,SMAD family member 4,hSMAD4 |
| 2 | B (D) | DNA (5'-D(P*AP*TP*GP*CP*GP*GP*GP*CP*GP*CP*GP*CP*CP*CP*GP*CP*AP*T)-3') | polymer | 18 | 5518.6 | 1 | Homo sapiens | ||
| 3 | C (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | D, E, F, G (A) | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 5 | H, I (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
| 6 | J (D) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 7 | K, L, M, N, O (D) | CALCIUM ION | non-polymer | 40.1 | 5 | Chemie (CA) | |||
| 8 | P, Q (A, D) | water | water | 18.0 | 92 | Chemie (HOH) |
Sequence modifications
A: 10 - 140 (UniProt: Q13485)
| PDB | External Database | Details |
|---|---|---|
| Gly 6 | - | expression tag |
| Ala 7 | - | expression tag |
| Met 8 | - | expression tag |
| Gly 9 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 20756.1 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 681.9 | |
| All* | Total formula weight | 21438.1 |
