5M8I

Solution structure of CUG-BP2 RRM3 in complex with 5'-UUUAA-3' RNA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	CUGBP Elav-like family member 2	polymer	114	12842.7	1	UniProt (O95319) Pfam (PF00076)	Homo sapiens (Human)	CELF-2,Bruno-like protein 3,CUG triplet repeat RNA-binding protein 2,CUG-BP2,CUG-BP- and ETR-3-like factor 2,ELAV-type RNA-binding protein 3,ETR-3,Neuroblastoma apoptosis-related RNA-binding protein,hNAPOR,RNA-binding protein BRUNOL-3
2	B (B)	RNA (5'-R(*UP*UP*UP*AP*A)-3')	polymer	5	1532.0	1		Homo sapiens

Sequence modifications

A: 22 - 114 (UniProt: O95319)

PDB	External Database	Details
Met 1	-	initiating methionine
Gly 2	-	expression tag
Ser 3	-	expression tag
Ser 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
His 10	-	expression tag
Ser 11	-	expression tag
Ser 12	-	expression tag
Gly 13	-	expression tag
Leu 14	-	expression tag
Val 15	-	expression tag
Pro 16	-	expression tag
Arg 17	-	expression tag
Gly 18	-	expression tag
Ser 19	-	expression tag
His 20	-	expression tag
Met 21	-	expression tag
Trp 114	Tyr 521	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	14374.6
All*	Total formula weight	14374.6

*Water molecules are not included.