5M7C
Blood group synthase AAGlyB in complex with UDP and cryoprotected with PEG 3350
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Histo-blood group ABO system transferase | polymer | 298 | 34654.0 | 2 | UniProt (P16442) Pfam (PF03414) | Homo sapiens (Human) | Fucosylglycoprotein 3-alpha-galactosyltransferase,Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase,Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase,Glycoprotein-fucosylgalactoside alpha-galactosyltransferase,Histo-blood group A transferase,A transferase,Histo-blood group B transferase,B transferase,NAGAT |
| 2 | C, H (A, B) | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
| 3 | D, I (A, B) | URIDINE-5'-DIPHOSPHATE | non-polymer | 404.2 | 2 | Chemie (UDP) | |||
| 4 | E, F (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
| 5 | G, J (A, B) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 6 | K, L (A, B) | water | water | 18.0 | 374 | Chemie (HOH) |
Sequence modifications
A, B: 64 - 354 (UniProt: P16442)
| PDB | External Database | Details |
|---|---|---|
| Met 57 | - | expression tag |
| Ala 58 | - | expression tag |
| Ile 59 | - | expression tag |
| Gly 60 | - | expression tag |
| Glu 61 | - | expression tag |
| Phe 62 | - | expression tag |
| Met 63 | - | expression tag |
| Gly 266 | Leu 266 | engineered mutation |
| Ala 268 | Gly 268 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 69308.0 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1322.6 | |
| All* | Total formula weight | 70630.6 |
