5M62

Structure of the Mus musclus Langerin carbohydrate recognition domain in complex with glucose

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	C-type lectin domain family 4 member K	polymer	151	17517.5	2	UniProt (Q8VBX4) Pfam (PF00059)	Mus musculus (Mouse)	Langerin
2	C, L (A, B)	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
3	D, E, F, G, H... (A, B)	GLYCEROL	non-polymer		92.1	8	Chemie (GOL)
4	J, Q (A, B)	HEXAETHYLENE GLYCOL	non-polymer		282.3	2	Chemie (P6G)
5	K, P (A, B)	beta-D-glucopyranose	non-polymer		180.2	2	Chemie (BGC)
6	O (B)	alpha-D-glucopyranose	non-polymer		180.2	1	Chemie (GLC)
7	R, S (A, B)	water	water		18.0	276	Chemie (HOH)

Sequence modifications

A, B: 194 - 331 (UniProt: Q8VBX4)

PDB	External Database	Details
Met 191	-	initiating methionine
Ala 192	-	expression tag
Gly 193	-	expression tag
Ser 308	Cys 308	engineered mutation
Gly 332	-	expression tag
Thr 333	-	expression tag
Trp 334	-	expression tag
Ser 335	-	expression tag
His 336	-	expression tag
Pro 337	-	expression tag
Gln 338	-	expression tag
Phe 339	-	expression tag
Glu 340	-	expression tag
Lys 341	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	35035.0
Non-Polymers*	Number of molecules	15
	Total formula weight	1922.0
All*	Total formula weight	36957.1

*Water molecules are not included.