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5M5Q

COPS5(2-257) IN COMPLEX WITH A AZAINDOLE (COMPOUND 4)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
COP9 signalosome complex subunit 5polymer25728951.01UniProt (Q92905)
Pfam (PF01398)
Homo sapiens (Human)Signalosome subunit 5,Jun activation domain-binding protein 1
2B
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
3C
(A)
1-[(3~{R})-3-(1~{H}-benzimidazol-2-yl)morpholin-4-yl]-3-[2-(4-methyl-2-phenyl-phenyl)-1~{H}-pyrrolo[2,3-b]pyridin-3-yl]propan-1-onenon-polymer541.61Chemie (7K1)
4D
(A)
(4S)-2-METHYL-2,4-PENTANEDIOLnon-polymer118.21Chemie (MPD)
5E
(A)
waterwater18.047Chemie (HOH)
Sequence modifications
A: 2 - 257 (UniProt: Q92905)
PDBExternal DatabaseDetails
Gly 1-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight28951.0
Non-Polymers*Number of molecules3
Total formula weight725.2
All*Total formula weight29676.2
*Water molecules are not included.

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PDB entries from 2024-11-20

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