5M5B
Crystal structure of Zika virus NS5 methyltransferase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | NS5 methyltransferase | polymer | 272 | 30355.7 | 2 | UniProt (H9A910) Pfam (PF01728) UniProt (by SIFTS) (A0A024B7W1) | Zika virus (ZIKV) | |
| 2 | C (A) | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 1 | Chemie (SAM) | |||
| 3 | D, E, F, G (A, B) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 4 | H (B) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | I (B) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 6 | J, K (A, B) | water | water | 18.0 | 381 | Chemie (HOH) |
Sequence modifications
A, B: 11 - 272 (UniProt: H9A910)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| Lys 2 | - | expression tag |
| His 3 | - | expression tag |
| His 4 | - | expression tag |
| His 5 | - | expression tag |
| His 6 | - | expression tag |
| His 7 | - | expression tag |
| His 8 | - | expression tag |
| Gly 9 | - | expression tag |
| Ser 10 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 60711.5 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 910.2 | |
| All* | Total formula weight | 61621.7 |
