5M5B
Crystal structure of Zika virus NS5 methyltransferase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | NS5 methyltransferase | polymer | 272 | 30355.7 | 2 | UniProt (H9A910) UniProt (by SIFTS) (A0A024B7W1) | Zika virus (ZIKV) | |
| 2 | C (A) | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 1 | Chemie (SAM) PubChem (5136) PubChem (34755) PubChem (58633578) PubChem (60038769) PubChem (73897310) PubChem (58766358) PubChem (87224684) PubChem (131697735) PubChem (9865603) PubChem (145712080) PubChem (12312798) PubChem (132988922) PubChem (134692588) PubChem (135030730) PubChem (140459785) PubChem (163046094) | |||
| 3 | D, E, F, G (A, B) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 4 | H (B) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) PubChem (753) | |||
| 5 | I (B) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) PubChem (312) | |||
| 6 | J, K (A, B) | water | water | 18.0 | 381 | Chemie (HOH) |
Sequence modifications
A, B: 11 - 272 (UniProt: H9A910)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| Lys 2 | - | expression tag |
| His 3 | - | expression tag |
| His 4 | - | expression tag |
| His 5 | - | expression tag |
| His 6 | - | expression tag |
| His 7 | - | expression tag |
| His 8 | - | expression tag |
| Gly 9 | - | expression tag |
| Ser 10 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 60711.5 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 910.2 | |
| All* | Total formula weight | 61621.7 |
