5M4C
Complex structure of human protein kinase CK2 catalytic subunit with a thieno[2,3-d]pyrimidin inhibitor crystallized under low-salt conditions
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Casein kinase II subunit alpha | polymer | 335 | 40066.7 | 1 | UniProt (P68400) Pfam (PF00069) | Homo sapiens (Human) | CK II alpha |
| 2 | B (A) | 3-[5-(4-methylphenyl)thieno[2,3-d]pyrimidin-4-yl]sulfanylpropanoic acid | non-polymer | 330.4 | 1 | Chemie (7EY) | |||
| 3 | C (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 4 | D, E (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 5 | F (A) | water | water | 18.0 | 228 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 40066.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 550.1 | |
| All* | Total formula weight | 40616.8 |
