5M05
Chicken smooth muscle myosin motor domain co-crystallized with the specific CK-571 inhibitor, MgADP form
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Myosin-11 | polymer | 800 | 91442.5 | 1 | UniProt (P10587) Pfam (PF02736) Pfam (PF00063) | Gallus gallus (Chicken) | Myosin heavy chain 11,Myosin heavy chain,gizzard smooth muscle |
| 2 | B (A) | 4-{[(2-chloro-3-fluorobenzyl)carbamoyl](methyl)amino}-3,4-dideoxy-5-O-(isoquinolin-3-ylcarbamoyl)-D-erythro-pentitol | non-polymer | 504.9 | 1 | Chemie (52E) | |||
| 3 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | D (A) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 5 | E (A) | water | water | 18.0 | 54 | Chemie (HOH) |
Sequence modifications
A: 1 - 790 (UniProt: P10587)
| PDB | External Database | Details |
|---|---|---|
| Ala 2 | Ser 2 | conflict |
| Arg 205 | Lys 205 | conflict |
| Thr 206 | Asp 206 | conflict |
| Pro 207 | Thr 207 | conflict |
| Ala 208 | Ser 208 | conflict |
| Ser 209 | Ile 209 | conflict |
| Leu 210 | Thr 210 | conflict |
| Lys 211 | Gln 211 | conflict |
| Val 212 | Gly 212 | conflict |
| His 213 | Pro 213 | conflict |
| Leu 214 | Ser 214 | conflict |
| Pro 216 | Ser 216 | conflict |
| Ala 411 | Arg 411 | conflict |
| Ala 412 | Asp 412 | conflict |
| Glu 415 | Gln 415 | conflict |
| Gly 791 | - | expression tag |
| Ser 792 | - | expression tag |
| Asp 793 | - | expression tag |
| Tyr 794 | - | expression tag |
| Lys 795 | - | expression tag |
| Asp 796 | - | expression tag |
| Asp 797 | - | expression tag |
| Asp 798 | - | expression tag |
| Asp 799 | - | expression tag |
| Lys 800 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 91442.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 956.4 | |
| All* | Total formula weight | 92399.0 |
