5LZG
Cholera toxin El Tor B-pentamer in complex with inhibitor PC262
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E (A, B, C, D, E) | Cholera enterotoxin subunit B | polymer | 103 | 11660.3 | 5 | UniProt (P01556) Pfam (PF01376) | Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) | Cholera enterotoxin B chain,Cholera enterotoxin gamma chain,Choleragenoid |
| 2 | F, I, J, L, N (A, B, C, D, E) | (2~{R},4~{S},5~{R},6~{R})-5-acetamido-2-[4-[3-[2-[(2~{S},3~{R},4~{R},5~{R},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]ethylamino]-3-oxidanylidene-propyl]-1,2,3-triazol-1-yl]-4-oxidanyl-6-[(1~{R},2~{R})-1,2,3-tris(oxidanyl)propyl]oxane-2-carboxylic acid | non-polymer | 621.6 | 5 | Chemie (7BN) | |||
| 3 | G (A) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) | |||
| 4 | H, M (A, D) | IMIDAZOLE | non-polymer | 69.1 | 2 | Chemie (IMD) | |||
| 5 | K (C) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 6 | O (E) | (4R)-2-METHYLPENTANE-2,4-DIOL | non-polymer | 118.2 | 1 | Chemie (MRD) | |||
| 7 | P, Q, R, S, T (A, B, C, D, E) | water | water | 18.0 | 575 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 58301.7 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 3592.6 | |
| All* | Total formula weight | 61894.3 |
