5LYQ
Crystal structure of the Retinoic Acid Receptor alpha in complex with a synthetic spiroketal agonist and a fragment of the TIF2 co-activator.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Retinoic acid receptor RXR-alpha | polymer | 240 | 26856.0 | 1 | UniProt (P19793) Pfam (PF00104) In PDB | Homo sapiens (Human) | Nuclear receptor subfamily 2 group B member 1,Retinoid X receptor alpha |
| 2 | B | HIS-LYS-ILE-LEU-HIS-ARG-LEU-LEU-GLN-ASP | polymer | 13 | 1579.9 | 1 | UniProt (by SIFTS) (Q15596) In PDB | Homo sapiens | |
| 3 | A | (2~{R})-6,6,9,9-tetramethylspiro[3,4,7,8-tetrahydrobenzo[g]chromene-2,2'-3,4-dihydrochromene]-6'-carboxylic acid | non-polymer | 406.5 | 1 | Chemie (7BE) | |||
| 4 | water | water | 18.0 | 165 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 28435.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 406.5 | |
| All* | Total formula weight | 28842.4 |
