5LXG

Revised crystal structure of the human adiponectin receptor 1 in an open conformation

Replaces:  3WXV

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Adiponectin receptor protein 1	polymer	305	35040.8	1	UniProt (Q96A54) Pfam (PF03006)	Homo sapiens (Human)	Progestin and adipoQ receptor family member I
2	B (H)	V REGION HEAVY CHAIN	polymer	119	13160.6	1		Mus musculus (House mouse)
3	C (L)	V REGION LIGHT CHAIN	polymer	107	11647.9	1		Mus musculus (House mouse)
4	D (A)	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
5	E, F (A, L)	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
6	G, H, I (A, H, L)	water	water		18.0	169	Chemie (HOH)

Sequence modifications

A: 89 - 375 (UniProt: Q96A54)

PDB	External Database	Details
Met -17	-	initiating methionine
Asp -16	-	expression tag
Tyr -15	-	expression tag
Lys -14	-	expression tag
Asp -13	-	expression tag
Asp -12	-	expression tag
Asp -11	-	expression tag
Asp -10	-	expression tag
Lys -9	-	expression tag
Glu -8	-	expression tag
Asn -7	-	expression tag
Leu -6	-	expression tag
Tyr -5	-	expression tag
Phe -4	-	expression tag
Gln -3	-	expression tag
Gly -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	59849.3
Non-Polymers*	Number of molecules	3
	Total formula weight	257.5
All*	Total formula weight	60106.8

*Water molecules are not included.