5LXD
Crystal structure of DYRK2 in complex with EHT 1610 (compound 2)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Dual specificity tyrosine-phosphorylation-regulated kinase 2 | polymer | 408 | 46969.3 | 2 | UniProt (Q92630) Pfam (PF00069) In PDB | Homo sapiens (Human) | |
2 | A, B | methyl 9-[(2-fluoranyl-4-methoxy-phenyl)amino]-[1,3]thiazolo[5,4-f]quinazoline-2-carboximidate | non-polymer | 383.4 | 2 | Chemie (7A7) | |||
3 | A, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 10 | Chemie (EDO) | |||
4 | water | water | 18.0 | 193 | Chemie (HOH) |
Sequence modifications
A, B: 73 - 479 (UniProt: Q92630)
PDB | External Database | Details |
---|---|---|
Ser 72 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 93938.6 | |
Non-Polymers* | Number of molecules | 12 |
Total formula weight | 1387.5 | |
All* | Total formula weight | 95326.1 |