5LX6
Human PARP10 (ARTD10), catalytic fragment in complex with PARP inhibitor Veliparib
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Poly [ADP-ribose] polymerase 10 | polymer | 191 | 21628.6 | 2 | UniProt (Q53GL7) Pfam (PF00644) | Homo sapiens (Human) | PARP-10,ADP-ribosyltransferase diphtheria toxin-like 10,ARTD10 |
| 2 | C, D (A, B) | (2R)-2-(7-carbamoyl-1H-benzimidazol-2-yl)-2-methylpyrrolidinium | non-polymer | 244.3 | 2 | Chemie (78P) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 360 | Chemie (HOH) |
Sequence modifications
A, B: 819 - 1007 (UniProt: Q53GL7)
| PDB | External Database | Details |
|---|---|---|
| Ser 817 | - | expression tag |
| Met 818 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 43257.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 488.6 | |
| All* | Total formula weight | 43745.8 |
