5LTW
Complex of human 14-3-3 sigma CLU1 mutant with phosphorylated heat shock protein B6
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, E, F, I... (A, B, E, F, I...) | 14-3-3 protein sigma | polymer | 234 | 26257.5 | 6 | UniProt (P31947) Pfam (PF00244) | Homo sapiens (Human) | Epithelial cell marker protein 1,Stratifin, CLU1 |
| 2 | C, D, G, H, K... (C, D, G, H, K...) | Heat shock protein beta-6 | polymer | 149 | 16245.4 | 6 | UniProt (O14558) Pfam (PF00525) Pfam (PF00011) | Homo sapiens (Human) | HspB6,Heat shock 20 kDa-like protein p20 |
| 3 | M, N, P, Q, S... (A, B, E, F, I...) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 6 | Chemie (TRS) | |||
| 4 | O, R, U (D, H, L) | NICKEL (II) ION | non-polymer | 58.7 | 3 | Chemie (NI) |
Sequence modifications
A, B, E, F, I, J: 1 - 231 (UniProt: P31947)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Pro -1 | - | expression tag |
| His 0 | - | expression tag |
| Ala 159 | Lys 159 | engineered mutation |
| Ala 160 | Lys 160 | engineered mutation |
| Ala 161 | Glu 161 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 255017.7 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 908.9 | |
| All* | Total formula weight | 255926.6 |
